For Patients - Lyndra

CHANGING THE PILL, NOT THE PATIENT

Providing the medicines patients want in a long-acting oral pill

Expecting perfect adherence to daily medication is simply unrealistic. Almost everyone struggles to remember their daily pills sometimes, even individuals with the best intentions to take their medications exactly as prescribed. The LYNX^® drug delivery platform promises to transform the patient experience, freeing people from the burden of daily pills and simplifying their lives. Research shows that nearly ~90% of patients and caregivers prefer oral pills over any other drug delivery method including injectables. Additionally, although they’d never heard of the concept before, ~80% of patients and caregivers find an oral weekly pill appealing.¹⁹ That is why Lyndra is focused on changing the pill, not the patient.

Research

Long-acting oral therapies could transform people’s relationships with medicine and improve their treatment outcomes – freeing people from the burden of daily pills, providing choice in medication delivery, improving adherence to prescribed medicines and simplifying people’s lives.”

Platform

Lyndra’s LYNX^® drug delivery platform has the potential for broad applicability across multiple therapeutic areas – including approved drugs and those currently in development.

Team

Lyndra has assembled a visionary and determined team that is passionate about transforming the patient experience.

Commitment to Patients

"The Swedish word “lindra” means to 'relieve, soothe or ease.' And that’s exactly what we at Lyndra are trying to do – to relieve suffering by making it easier for people to take their medications… What makes Lyndra such a great company is that everyone is so committed to improving patient care. I know that what I do today is an incremental step toward potentially changing the lives of people everywhere. It could be someone who lives down the street from me, or someone who lives a world away, or a family member, or me!"

Erik Ryde

Associate Director, Technical Operations

Clinical Trials

Who Lyndra Helps

People living with schizophrenia

Schizophrenia is a serious mental health condition that affects how a person thinks, feels and behaves. A stable and fulfilling life for someone living with schizophrenia is possible with the correct treatment and support. However, while initial diagnosis and treatment for schizophrenia is high, it is estimated that only ~60% of diagnosed US adults receive consistent and appropriate care year-over-year.²⁰ For patients taking risperidone, weekly dosing (vs. daily dosing) has the potential to increase medication adherence, prevent relapses and improve outcomes.

People living with bipolar 1 disorder

According to the National Institutes of Mental Health, bipolar 1 disorder is a mental health condition that causes unusual shifts in mood, energy, activity levels, concentration and the ability to carry out day-to-day tasks with manic episodes that last at least 7 days, or by manic symptoms that are so severe that the person needs immediate hospital care. Although the symptoms may vary over time, bipolar 1 disorder usually requires lifelong treatment.²¹ Following a prescribed treatment plan can help people manage their symptoms and improve their quality of life. Lyndra believes that, for patients taking risperidone, weekly dosing (vs. daily dosing) has the potential to increase medication adherence, prevent relapses and improve outcomes.

~ 91 %

of people living with schizophrenia or bipolar disorder self-reported at least sometimes struggling with medication adherence, according to a recent study conducted on behalf of Lyndra.²²

~ 54 %

of people living with schizophrenia or bipolar disorder and their caregivers reported low medication adherence, according to the same study that used a validated Morisky scale.²³

Stay Connected

Interested in staying updated on the work that Lyndra is doing? Follow Lyndra on social media.

Citations

19. Patient Unmet Needs Survey (Q3’21; n=1645 patients and caregivers)

20. The Treatment Advocacy Center, “Schizophrenia – Fact Sheet,” https://www.treatmentadvocacycenter.org/evidence-and-research/learn-more-about/25-schizophrenia-fact-sheet, accessed November 6, 2021.

21. National Association of Mental Illness, “Bipolar Disorder,” https://www.nami.org/About-Mental-Illness/Mental-Health-Conditions/Bipolar-Disorder, accessed January 4, 2022.

22. Patient Unmet Needs Survey (Q3’21; n=1645 patients and caregivers)

23. Patient Unmet Needs Survey (Q3’21; n=1645 patients and caregivers)