May 8, 2018

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The "Pill of Tomorrow, Here Today"

OVERVIEW

Currently, medication non-adherence costs more and affects more people than any single disease.  Approximately 70% of American adults suffer from at least one chronic disease and ~50% of medications for chronic disease are not taken as prescribed[1], and hence the U.S. suffers significant associated costs, both in terms of dollars and lives.

These costs are estimated to amount to $100-$289 billion of avoidable spend and more than 125,000+ deaths per year resulting from medication non-adherence[2]

Lyndra's solution

Lyndra is making daily pills a thing of the past. 

Instead of having to take medications daily or more frequently, Lyndra’s oral, ultra-long-acting, sustained-release therapies, could allow patients to take medication weekly, or even monthly. The aim is to improve medication adherence, health outcomes, and help lower the cost of care.

CHANGE THE PILL, NOT THE PATIENT

Lyndra’s near-term focus is on addressing health conditions where therapeutic need is largely unmet and where patient non-adherence has been well documented to adversely affect health outcomes. The current pipeline includes therapies for Alzheimer’s disease, HIV, opioid use disorder and schizophrenia as well as a new once-monthly option for oral contraception.

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REFERENCES : [1] https://www.cdc.gov [2] Rosenbaum, L., Shrank, W. (2013).The NEJM 369(8), 694-695.