May 8, 2018



Lyndra Therapeutics Takes on Opioid Use Disorder with Long-Acting Oral Dosage Form
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Our Vision

Ultra-long-acting oral medicines will remove the burden of daily pills and improve compliance, health, and quality of life for patients and caregivers.

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Our Approach

Human nature is a hard thing to change. At Lyndra, we’ve turned the problem on its head. We ask, “What if we stopped trying to change the patient, and changed the pill instead?

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Our Therapies

Our ultra-long-acting oral medicines provide better health outcomes and quality of life, reduced side effects, improved drug efficacy, slowed spread of disease, and lower health costs.

Ultra-Long-Acting Oral Dosing is Achievable

Our Team has developed the first ultra-long-acting pill that lasts a week or longer and can provide a wide range of medicines in a familiar oral capsule form. Once inside the stomach, the capsule delivers steady amounts of medicine for seven days or more.  Our once-weekly product has safely demonstrated gastric residence with predictable pharmacokinetics in humans.  There are no other oral products which provide ultra-long-acting therapeutic coverage or a controlled, steady delivery of medicine which can reduce side effects and improve drug efficacy, resulting in measurable health outcomes.

  • Advantages in systemic, non-systemic, and local target delivery due to continuous & steady delivery
  • Possibility of reducing total dose while maintaining efficacy (non-inferiority)
  • Reducing Cmax can improve side effects
  • Forgiveness if delayed administration

  • Reduced healthcare costs through better pharmacology and measurable health outcomes
  • Patient freedom form the burden of daily medications

  • Adaptable for wide range of single agents (small molecule / peptide) and combinations
  • Discreet user controlled administration
  • Reduced pill burden
  • Reduced caregiver burden

  • Superior Pharmacology for existing Agents
  • Loss of Exclusivity (LOE)
  • Combination Products
  • Local GI Delivery
  • Non-systemic Delivery Enhanced Continuous Release

"Extended-release oral systems will revolutionize current clinical-care models and maximize effective treatment for a wide range of diseases in a variety of clinical settings."​

Robert Langer & Giovanni Traverso